莫冬亮-pg电子游戏试玩平台网站
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莫冬亮-pg电子游戏试玩平台网站

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莫冬亮

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基本介绍

莫冬亮博士,广西师范大学教授,博士生导师。2006年毕业于南开大学化学系,2011年于中国科学院上海有机化学研究所获得有机化学博士学位,师从有机化学家戴立信院士和侯雪龙研究员。2011-2014年在美国university of illinois at chicago进行三年博士后研究。2014年9月以漓江学者引进至广西师范大学化学与药学学院。2014年11月入选广西高校引进海外高层次人才计划第二批。2015年12月破格晋升为教授并遴选为博士生导师,主要从事有机合成、金属有机化学及药物化学。以第一作者或通讯作者在angew.chem.int.ed.; org.lett.; chem. eur. j., j.org.chem. organometallics, synthesis等国际著名期刊发表sci论文30余篇。目前主持国家自然科学基金3项(青年、地区、面上),广西自然科学基金2项,广西高层次人才计划基金1项,重点实验室主任基金1项。2016年获得广西杰出青年基金,并获得2016年德国thieme chemistry journal award,2017年广西高等学校“千名中青年骨干教师”第一期培育计划。

研究方向

mo课题组详细pg电子官网主页:

学历背景

2011.8-2014.8 美国university of illinois at chicago,博士后(合作导师:prof. laura anderson)

2006.9-2011.7中国科学院上海有机化学研究所,获博士学位(导师:戴立信 院士和侯雪龙 研究员)

2002.9-2006.7 南开大学化学系化学专业,获学士学位(导师:徐善生和王佰全 教授)


工作经历

2016.01  被遴选为广西师范大学博士生导师

2015.12  破格晋升为教授

2014.09  广西师范大学化学与药学学院,漓江学者,硕士生导师


社会任职

是国际著名有机化学期刊acs catalysis, organic letters,  adv. synth. catal., j. org. chem.;  eur. j. org. chem. synthesis, chemistryselect等审稿人。

讲授课程

本科生《有机化学》、《有机合成》、《有机专论》、《化学专业英语》以及《有机化学基础实验2》。研究生的《有机合成》和《高等有机》。

论著专利

2014年11月成立课题组以来发表的sci论文 (*为通讯作者, †为共同第一作者):

51. cui wei,jie-feng zhu, jin-qi zhang,qi deng,and dong-liang mo*,synthesis of spirofluorenyl-beta-lactams through cycloaddition and ring contraction from n-aryl fluorenone nitrones and methylenecyclopropanes, adv. synth.catal.2019, major revision.

50.hong-yan bi,min du,cheng-xue pan,* yuhong xiao, gui-fa su,* and dong-liang mo*, nickel(ii)-catalyzed [5 1] annulations of 2-carbonyl-1-propargylindoles with hydroxylamine to synthesize pyrazino[1,2-a]indole-2-oxides in water,j. org.chem. 2019, major revision.

49. hong-ping zhao, xiao-pan ma, shu-min nie, yuhong xiao, and dong-liang mo*, synthesis of chromeno[4,3-b]quinolines and spirobenzofuran-3,3'-quinolines through silver-mediated appel reaction/c-br bond cleavage/double selective rearrangement sequence, org. chem. front., 2019, 6, doi: 10.1039/c9qo00417c.

48. feng-ping liu†(2014级独秀班本科), hong-ping zhao†,shuang tan, xiuqiang lu, dong-liang mo*, sodium hydride promoted c−c/c−o bond cleavage to prepare 2-(3-methyleneindolin-2-yl)phenols, synthesis, 2019, has been accepted.

47.jing-mei yuan†, kai wei†, guo-hai zhang, nan-ying chen, xin-wei wei,cheng-xue pan*, dong-liang mo*, gui-fa su*,cryptolepine and aromathecin based mimics as potent g-quadruplexbinding,dna-cleavage and anticancer agents: design, synthesis and dna targeting-induced apoptosis,eur. j. med. chem. 2019, 169, 144-158.

46. qing-qing liu†,ke lu†,hai-miao zhu, shi-lin kong,jing-mei yuan, guo-hai zhang, nan-ying chen, chen-xi gu, cheng-xue pan,* dong-liang mo,* and gui-fa su*,identification of 3-(benzazol-2-yl)quinoxaline derivatives as potent anticancer compounds: privileged structure-based design, synthesis, and bioactive evaluation in vitro and in vivoeur. j. med. chem. 2019, 165, 293-308.

45. ning zou†, ji-wen jiao† (2015级独秀班本科生), yu feng, cheng-xue pan, cui liang, gui-fa su,* and dong-liang mo*,  iron(iii)/copper(ii)-cocatalyzed cycloaddition/[3,3]-rearrangement /n−o bond cleavage to prepare polysubstituted pyrrolizines from n-vinyl-a,β-unsaturated nitrones and activated alkynes, org. lett. 2019, 21, 481-485.

44. si-yi wu†(2014级独秀班本科生), wei-li chen,† xiao-pan ma, cui liang, gui-fa su,* and dong-liang mo*, copper-catalyzed [3 2] cycloaddition and interrupted fischer indolization to prepare polycyclic furo[2,3-b]indolines from n-aryl isatin nitrones and methylenecyclopropanes,  adv. synth. catal. 2019, 361, 965-970.

43. yan-xiao jiao, lin-su wei, chun-yang zhao, kai wei, dong-liang mo,* chen-xue pan,* and gui-fa su*, isobutyl nitrite-mediated synthesis of quinoxalines through double c−h bond amination of n-aryl enamines,  adv. synth. catal.2018, 360, 4446-4451.

42. xiao-pan ma, liang-gui li, hong-ping zhao, min du, cui liang, and dong-liang mo*, formal [7 2] cycloaddition of arynes with n-vinyl-ɑ,β-unsaturated nitrones: facile synthesis of benzoxazonines and their n−o bonds cleavage, org. lett.2018, 20, 4571-4574 (if =6.57, sci一区).

41. ji-wen jiao†(2015级独秀班本科), hong-yan bi†, pei-sen zou, zhi-xin wang*, cui liang, and dong-liang mo*, copper-mediated difunctionalization of alkenylboronic acids: synthesis of ɑ-imino ketones, adv. synth. catal.2018, 360, 3254-3259 (if = 5.64, sci一区).

40. wei-li chen,† si-yi wu†(2014级独秀班本科), xue-ling mo, liu-xu wei, cui liang, and dong-liang mo*, synthesis of 2-aminobenzonitriles through nitrosation reaction and sequential iron(iii)-catalyzed c−c bond cleavage of 2-arylindoles, org. lett. 2018, 20, 3527-3530 (if = 6.57, sci一区)

39. lin-su wei,guo-xue he,xiang-fei kong, cheng-xue pan*, dong-liang mo*,and gui-fa su*, gold(iii)-catalyzed selective cyclization of alkynyl quinazolinone tethered pyrroles: synthesis of fused quinazolinone scaffolds,  j. org. chem., 2018, 83, 6719-6727. (if = 4.84, sci二区)

38. chun-hua chen, qing-yan wu (2016级独秀班本科), cui wei, cui liang, gui-fa su*, and dong-liang mo*, iron(iii)-catalyzed selective n−o bond cleavage to prepare tetrasubstituted pyridines and 3,5-disubstituted isoxazolines from n-vinyl-ɑ,β-unsaturated ketonitrones, green. chem. 2018, 20, 2722-2729 (if = 9.125, 被green chemistry选为封面, sci一区).

37. chun-yang zhao,† kun li† (2015级独秀班本科), yu pang, jia-qing li, cui liang, gui-fa su*, and dong-liang mo*, iodine(iii) reagent-mediated intramolecular amination of 2-alkenylanilines to prepare indoles, adv. synth. catal.2018, 360, 1919-1925 (if = 5.64, sci一区).

36. hong-yan bi,† feng-ping liu† (2014级独秀班本科), cui liang, gui-fa su*, and dong-liang mo*, a tunable route to prepare ɑ,β-unsaturated esters and ɑ,β-unsaturated-γ-keto esters through copper-catalyzed coupling of alkenyl boronic acids with phosphorus ylides, adv. synth. catal.2018, 360, 1510-1516 (if = 5.64, sci一区)

35. xiang-fei kong, feng zhan, guo-xue he, cheng-xue pan, chen-xi gu, ke lu, dong-liang mo*, and gui-fa su*, gold-catalyzed selective 6-exo-dig and 7-endo-dig cyclizations of alkynyl-tethered indoles to prepare rutaecarpine derivatives,  j. org. chem., 2018, 83, 2006-2017. (if = 4.84, sci二区)

34. xiao-hua li† (2013级独秀班本科生), ai-hui ye† (2014级化学班本科生), cui liang, and dong-liang mo*, substituent effects of 2-pyridones on selective o-arylation with diaryliodonium salts: synthesis of 2-aryloxypyridines under metal-free conditions, synthesis2018, 50, 1699-1710. (if = 2.65, sci三区).

33. xue-ling mo†(2013级独秀班本科生), chun-hua chen†, cui liang, and dong-liang mo*, copper-catalyzed carbonyl group controlled coupling of isatin oximes with arylboronic acids to prepare n-aryl oxindole nitrones, eur. j. org. chem.2018, 150-159. (if= 2.83, 被主编选为特色封面,sci三区).

32. xiao-pan ma, kun li (2015级独秀班本科生), si-yi wu, cui liang, gui-fa su*, and dong-liang mo*, construction of 2,3-quaternary fused indolines from alkynyl tethered oximes and diaryliodonium salts through a cascade strategy of n-arylation/cycloaddition/[3,3]-rearrangement, green chemistry, 2017, 19, 5761-5766. (if = 9.125, 被green chemistry选为封面和2017年度的hot article之一,, sci一区).

31. wei-min shi,† xiao-hua li† (2013级独秀班本科生), cui liang, and dong-liang mo*, base-free selective o-arylation and sequential [3,3]-rearrangement of amidoximes with diaryliodonium salts: synthesis of 2-substituted benzoxazoles, adv. synth. catal.2017, 359,4129-4135. (if = 5.64, sci一区).

30. ning zou, ji-wen jiao (2015级独秀班本科生), yu feng (2015级制药工程本科生), chun-hua chen, cui liang, gui-fa su,*, and dong-liang mo*, diastereoselective synthesis of nine-membered heterocycles via the cycloaddition and sequential rearrangement of n-vinyl nitrones with isocyanates, adv. synth. catal.2017, 359, 3545-3550. (if = 5.64, sci一区).

29. wei-min shi†, feng-ping liu† (2014级独秀班本科生), zhi-xin wang, hong-yan bi, cui liang, li-ping xu*, gui-fa su*, and dong-liang mo*. synthesis of 1-vinyl/aryl benzotriazole 3-oxides through copper-catalyzed c-n bond coupling reaction, adv. synth. catal.2017, 359, 2741-2746. (if = 5.64, sci一区)

28. chun-hua chen†, qing-qing liu†, xiao-pan ma, yu feng (2015级制药工程本科生), cui liang, cheng-xue pan, gui-fa su*, and dong-liang mo*, copper-catalyzed selective n-vinylation of 3-(hydroxyimino)indolin-2-ones with alkenyl boronic acids: synthesis of n-vinyl nitrones and spirooxindoles, j. org. chem., 2017, 82, 6417-6425. (if = 4.84, sci二区)

27. xiao-pan ma, feng-ping liu (2014级独秀班本科生),  and dong-liang mo*, recent advances in chan-evans-lam coupling reaction, chin. j. org. chem.2017, 37, 1069-1087.(if = 1.3, sci四区)

26. yan-xiao jiao, ling-ling wu, hai-miao zhu, jiang-ke qin, cheng-xue pan,* dong-liang mo*, and gui-fa su*, tandem c−n bond formation through condensation and metal-free n-arylation: protocol for synthesizing diverse functionalized quinoxalines, j. org. chem., 2017, 82, 4407-4414. (if = 4.84, sci二区)

25. si-yi wu (2014级独秀班本科生)†,, xiao-pan ma†,, cui liang, and dong-liang mo*, synthesis of n-aryl oxindole nitrones through metal-free selective n-arylation process, j. org. chem., 2017, 82, 3232-3238. (if = 4.84, sci二区)

24. xiao-pan ma, jie-feng zhu (2014级独秀班本科生), si-yi wu (2014级独秀班本科生), chun-hua chen, ning zou, cui liang, gui-fa su,* and dong-liang mo*,   cycloaddition of fluorenone n-aryl nitrones with methylenecyclopropanes and sequential [1,3]-rearrangement: an entry to synthesis of spirofluoenylpiperidin-4-ones, j. org. chem.2017, 82, 502-511.(if = 4.84, sci二区)

23. yan-xiao jiao, xiao-pan ma, gui-fa su*, and dong-liang mo*, recent advances in arylation and alkenylation of n-o bonds, synthesis 2017, 49, 933-959. (if = 2.65, sci三区)

22. zhi-xin wang,  wei-min shi,   hong-yan bi (2012级化学班本科生), xiao-hua li,  gui-fa su*,  and dong-liang mo*, synthesis of n-(2-hydroxyaryl)-benzotriazoles via metal-free o-arylation and n-o bond cleavage, j. org. chem2016, 81,8014 (if = 4.72, sci二区)

21. chun-yang zhao†, liang-gui li † (共同一作、2013级独秀班本科生 ), qing-rong liu, cheng-xue pan, gui-fa su* and dong-liang mo*. synthesis of β-acetoxy alcohols by phi(oac)2-mediated metal-free diastereoselective β-acetoxylation of alcohols, organic & biomolecular chemistry 2016, 48, 6795-6803. (if = 3.56, sci二区)

20. xiao-hua li (2013级独秀班本科生), liang-gui li, xue-ling mo, and dong-liang mo*. transition metal-free synthesis of thiocyanato- or nitro-arenes through diaryliodonium salts,  synthetic communications 2016, 46, 963-970.(if = 1.0, sci四区)

19. wei-min shi, xiao-pan ma, gui-fa su* and dong-liang mo* “new developments of ketonitrones in organic synthesis” organic chemistry frontiers 2016, 3, 116-130. (if = 4.68, sci二区) 

18. wei-min shi, xiao-pan ma, cheng-xue pan, gui-fa su* and dong-liang mo* “tandem c−o and c−n bonds formation through o-arylation and [3,3]-rearrangement by diaryliodonium salts: synthesis of n-aryl benzo[1,2,3]triazin-4(1h)-one derivatives” j. org. chem2015, 80 (21), 11175-11183 (if = 4.72, sci二区)

17. xiao-pan ma, wei-min shi, xue-ling mo (2013级独秀班本科生), xiao-hua li (2013级独秀班本科生), liang-gui li (2013级独秀班本科生), cheng-xue pan, bo chen*, gui-fa su* and dong-liang mo* “synthesis of α,β-unsaturated n-aryl ketonitrones from oximes and diaryliodonium salts: observation of a metal free n-arylation process” j. org. chem. 2015, 80(20), 10098-10107 (if = 4.72, sci二区)

16. qing-rong liu, cheng-xue pan, xiao-pan ma, dong-liang mo* and gui-fa su*. “(diacetoxyiodo)benzene (dib) -mediated reaction of ethynylcarbinols: an entry to α,α’-diacetoxy ketones and glycerol derivatives” j. org. chem. 2015, 80 (12), 6496-6501 (if = 4.72, sci二区)


已授权的中国发明专利

1)莫冬亮,石维敏,马小盼,闭红艳,苏桂发,陈春华,邹宁。n-烯基苯并三唑类氮氧衍生物及其制备方法和应用。发文日:2018.09.21;申请国别:中国;专利号:201610317256.4

2)莫冬亮,石维敏,马小盼,闭红艳,苏桂发,陈春华,邹宁。n-芳基苯并三唑类氮氧衍生物及其合成方法。发文日:2018.09.21;申请国别:中国;专利号:201610315960.6

3)莫冬亮,邹宁,陈春华,冯钰,苏桂发。1-氧-2,8-二氮杂环壬烷衍生物及其合成方法。申请时间:2016.09.18;申请国别:中国;申请号:201610826407.9

4)莫冬亮,陈春华,马小盼,刘凤萍,潘毓敏,苏桂发。2,3-吲哚二酮-3-n-烯基硝酮衍生物及其合成方法和应用。申请时间:2016.09.26;申请国别:中国;申请号:201610851288.2

5)莫冬亮, 马小盼,吴思仪,陈威利,苏桂发。2,3-稠环吲哚啉衍生物及其合成方法和应用。申请时间:2017.06.29;申请国别:中国;申请号:201710518658.5

 

 

获奖情况

2017.12 入选广西高等学校“千名中青年骨干教师培育计划”第一期培育计划

2017.05  获得广西师范大学第十一届“十佳青年”称号

2016.10 获得广西自然科学基金杰出青年基金资助

2015.12 荣获2016年度德国thieme chemistry journals award期刊奖 (2016年全球约有70名有机合成领域青年学者入选)

2014.11 入选广西高校海外高层次人才

2014.09 广西师范大学漓江学者




其他

本课题组每年接收1名博士、2-3名研究生(接受第一志愿或调剂)及对科研感兴趣的本科生

欢迎热爱有机化学的有志青年加入mo group!!!

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