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点击数:7738 来源:化学与药学学院 作者: 录入:人员机构 更新时间:2018-11-23



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基本介绍

博士,教授。20126月毕业于中南大学,获工学博士学位。20127月到广西师范大学工作,2013年晋升副教授。2017年破格晋升教授。2016年入选广西师范大学拔尖人才计划,2017年入选广西高等学校千名中青年骨干教师培育计划人选,2018年被评为广西师范大学优秀教师,2019年入选广西十百千人才工程第二层次人选,广西青年特聘专家,2019-2020年到美国stanford university作访问研究。先后主持国家自然科学基金3项、广西自然科学基金项目2项,参与国家自然科学基金及省部级科研项目多项。迄今,已在anal. chem., chem. commun., biosen. bioelectron., chem. eur. j., sensor actuat. b-chem., j. chromatogr. a, microchim. acta, anal. chim. acta等国外学术期刊上发表sci收录论文80余篇。曾获2018年度广西科学技术奖(自然科学类)一等奖(第一完成人)、2014年度广西科学技术奖(自然科学类)一等奖(第三完成人)、第十四届广西青年科技奖(2017年)、广西自然科学优秀论文二等奖2项(2011年、2012年)。曾任中国青年科技工作者协会第六届理事会理事、front. chem.客座编委,现为acs nano, small, theranostics, nanoscale, anal. chem., chem. commun., biosen. bioelectron., expert opin. drug. del., sensor actuat. b-chem., microchim. acta, anal. chim. acta20余种期刊审稿人。

研究方向

生物传感器、药物筛选及载药系统研究

代表性论文

1.  jiayao xu, lina fang, ming shi, yong huang,* lifang yao, shulin zhao,* liangliang zhang, hong liang,* a peptide-based four-color fluorescent polydopamine nanoprobe for multiplexed sensing and imaging of proteases in living cells.  chemical communications, 2019, 55(11): 1651-1654.

2. lifang yao, jiayao xu, ming shi, yong huang,* lina fang, shulin zhao,* zhen-feng chen, hongliang,* polydopamine nanoparticle-based multicolor proximity immunoassays for ultrasensitive, multiplexed analysis of proteins using isothermal quadratic amplification.  sensors and actuators b: chemical, 2019, 282: 626-635.

3. jiayao xu, ming shi, wenting chen, yong huang,* lina fang, lifang yao, shulin zhao,* zhen-feng chen, hong liang,* a gold nanoparticle-based four-color proximity immunoassay for one-step, multiplexed detection of protein biomarkers using ribonuclease h signal amplification. chemical communications, 2018, 54, 2719-2722.

4. yong huang,* huakui huang, jian qin, xiaoqian liu, shulin zhao,* zhen-feng chen, hong liang,* a graphene oxide-based multiplexed fluorescence assay for the detection of protein kinase activity in cell lysates and the evaluation of protein kinase inhibition. sensors and actuators b: chemical, 2017, 238, 908-916.

5. yong huang,* xiaoqian liu, huakui huang, jian qin, liangliang zhang, shulin zhao,* zhen-feng chen, hong liang,* attomolar detection of proteins via cascade strand-displacement amplification and polystyrene nanoparticle enhancement in fluorescence polarization aptasensors. analytical chemistry, 2015, 87, 8107-8114

6. yong huang,* xiaoqian liu, liangliang zhang kun hu, shulin zhao,* baizong fang, zhen-feng chen, hong liang,* nicking enzyme and graphene oxide-based dual signal amplification for ultrasensitive aptamer-based fluorescence polarization assay.  biosensors and bioelectronics, 2015, 63, 178-184.

7. yong huang, ming shi, limin zhao, shulin zhao*, kun hu, zheng-feng chen, jia chen, hong liang,* carbon nanotube signal amplification for ultrasensitive fluorescence polarization detection of dna methyltransferase activity and inhibition. biosensors and bioelectronics, 2014, 54, 285-291.

8. yong huang, shulin zhao,* zhen-feng chen, ming shi, hong liang,* amplified fluorescence polarization aptasensors based on structure-switching-triggered nanoparticles enhancement for bioassays. chemical communications, 2012, 48,7480-7482.

9. yong huang, shulin zhao,* zhen-feng chen, ming shi, jia chen, hong liang,* an amplified chemiluminescence aptasensor based on bi-resonance energy transfer ongold nanoparticles and exonuclease iii-catalyzed target recycling. chemical communications, 2012, 48,11877-11879.

10. yong huang, shulin zhao,* yi-ming liu, jia chen, zhen-feng chen, ming shi, hong liang,* an amplified single-walled carbon nanotube-mediated chemiluminescence turn-on sensing platform for ultrasensitive dna detection. chemical communications, 2012, 48,9400-9402.

11. yong huang, shulin zhao,* zhen-feng chen, yan-cheng liu, hong liang,* ultrasensitive endonuclease activity and inhibition detection using gold nanoparticle-enhanced fluorescence polarization. chemical communications, 2011, 47,4763-476;

12. yong huang, shulin zhao,* ming shi, jia chen, zhen-feng chen, hong liang,* intermolecular and intramolecular quencher based quantum dot nanoprobes for multiplexed detection of endonuclease activity and inhibition. analytical chemistry, 2011, 83, 8913-8918.








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